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Updated: Jan 16, 2026

Retroviral Transduction of Bone Marrow Progenitor Cells to Generate T-cell Receptor Retrogenic Mice
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有条件生成真实抗原特异性T细胞受体序列

Dhuvarakesh Karthikeyan1,2,3,4, Sarah N Bennett1,5,6, Amy G Reynolds5

  • 1Personalized Immunotherapy Research Lab, University of North Carolina at Chapel Hill, Chapel Hill, NC USA.

Nature machine intelligence
|September 29, 2025
PubMed
概括

我们开发了TCR-TRANSLATE,这是一个新的AI框架,用于设计T细胞受体 (TCR) 序列. 我们的模型成功设计了一种针对癌症抗原的功能性TCR,推进了个性化免疫疗法.

关键词:
适应性免疫是一种适应性免疫.机器学习是机器学习.

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