下肢压力骨折在甲状腺酸诱导的骨质病:一个案例报告
Shuji Nagata1, Miyuki Sawano1, Yuki Shouji1
1Department of Radiology, Kurume University School of Medicine, 67 Asahi-Machi, Kurume, Fukuoka 830-0011, Japan.
Radiology case reports
|September 29, 2025
概括
这项案例研究突出了为风湿性关节炎和白血病治疗甲状腺酸盐 (MTX) 的患者的超慢性压力骨折. MTX诱导的骨质病症可能导致双边下肢骨折,需要临床意识.
科学领域:
- 整形外科 整形外科 整形外科
- 类风湿病学 类风湿病学
- 放射学 放射学是一门学科.
背景情况:
- 甲托雷克萨特 (MTX) 通常用于类风湿性关节炎 (RA) 和急性淋巴细胞白血病 (ALL).
- 骨质炎是长期MTX治疗的潜在副作用.
- 压力骨折在运动员中很常见,但在患有潜在疾病的患者中也可能发生.
研究的目的:
- 报告一种罕见的超慢性应力骨折病例.
- 为了突出MTX诱导的骨质病和压力骨折之间的关联.
- 提高临床医生和放射科医生对这种潜在并发症的认识.
主要方法:
- 一个61岁妇女的病例报告.
- 病史和治疗的审查 (低剂量MTX治疗RA和ALL).
- 磁共振成像 (MRI) 用于诊断下肢压力骨折.
主要成果:
- 患者患有双边下肢压力骨折,包括远距离的小腿骨转移,骨和骨.
- 核磁共振扫描显示了压力骨折的特征发现,包括状病变和骨髓胀.
- 骨折发生在一个12个月的时间内顺序发生 (超时).
结论:
- 低剂量的甲状腺素可以诱导骨质病,导致压力骨折.
- 下肢的超慢性压力骨折是一种罕见但显著的并发症.
- 临床医生和放射科医生应考虑MTX诱导的骨质疏松症患者呈现出无法解释的脚或下肢疼痛.
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