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Updated: Jan 16, 2026

Development of an Ethanol-induced Fibrotic Liver Model in Zebrafish to Study Progenitor Cell-mediated Hepatocyte Regeneration
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Development of an Ethanol-induced Fibrotic Liver Model in Zebrafish to Study Progenitor Cell-mediated Hepatocyte Regeneration

Published on: May 13, 2016

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4EBP1酸化介导TGF-β1诱导的肝纤维化,并上调HIF-1α表达

Yue Shi1, Zhandong Lin1,2,3, Congyue Zhang1,2,3

  • 1Department of Internal Medicine, Hebei Medical University, Shijiazhuang, Hebei, China.

iScience
|September 29, 2025
PubMed
概括

向化真核转化启动因子4E结合蛋白1 (p-4E-BP1) 可能治疗肝纤维化. 这项研究揭示了p-4E-BP1是肝星细胞激活和纤维化发展的关键因素.

关键词:
生物化学 生物化学细胞生物学 细胞生物学纤维化 纤维化 纤维化

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