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增强-酸盐囊的扩散通道,用于微生物封装

Bilyamin Abdulmumin¹, Ismaila Mudi², Abdulalim Ibrahim^3,4

¹Department of Chemical Engineering Faculty of Engineering Ahmadu Bello University Zaria Nigeria.

Engineering in life sciences

|September 29, 2025

概括

这项研究引入了新型的酸囊,具有增强的扩散通道,用于微生物细胞固定. 使用葡萄糖作为孔形成剂显著改善了质量转移,有利于发酵过程.

科学领域:

生物材料工程生物材料工程
化学工程是化学工程的重要组成部分.
生物技术是生物技术.

背景情况:

藻酸盐囊在发酵中用于细胞封装,有助于连续过程和细胞恢复.
传统的囊表现出差的扩散,阻碍了基板和产品的运输.
改善扩散对于生物过程中有效的微生物细胞固定至关重要.

研究的目的:

开发具有增强扩散通道的新型氧化涂层酸盐囊.
为了研究一个孔隙形成剂对囊扩散特性的影响.
优化囊设计,以改善发酵中的质量转移.

主要方法:

使用CaCl2和CMC滴滴法制造藻酸盐囊.
使用水解的3-aminopropyl triethoxysilane,应用传统的二氧化涂层 (G-0).
引入葡萄糖作为多孔形成剂 (PFA) 在不同的数量 (0.75,1.5,3 g) 创建修改的囊 (G-0.75,G-1.5,G-3).

主要成果:

包括PFA在内的G-3囊表现出最高的扩散系数 (7.77±0.57) 在313.15K的温度下).
这与传统的G-0囊相比是一个显著的改进 ( $(3.04 \pm 0.09)\times10^{- 3 m m^{2} /mo>).}$
PFA有效地增强了膜的多孔性和扩散性.

结论:

开发的含有PFA的藻酸囊显示出显著改善的扩散特性.
这种增强对于微生物细胞固定化的有效质量转移至关重要.
这些新的囊有望促进发酵过程和其他生物转化应用.

关键词:

-酸盐囊酸盐囊扩散系数扩散系数发酵发酵发酵发酵这是一种微生物封装.有孔的二氧化涂层.

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