重新连接C型肝炎患者失去随访 - - 一个有针对性的战略
Antonio Olveira1, Raquel Domínguez-Hernández2, Susana Cano3
1Gastroenterology, Hospital Universitario La Paz.
Revista espanola de enfermedades digestivas
|September 29, 2025
概括
双模式策略有效地重新参与了被诊断出患有C型肝炎病毒 (HCV) 的患者,这些患者已经失去了随访. 这种方法促进了获得直接作用抗病毒药物 (DAA) 治疗的机会,这对于消除HCV的努力至关重要.
科学领域:
- 肝病学和传染病的研究
- 公共卫生干预措施 公共卫生干预措施
- 患者重新参与战略 患者重新参与策略
背景情况:
- 肝炎C病毒 (HCV) 感染导致全球肝病负担显著.
- 直接作用抗病毒药物 (DAA) 提供高治愈率,但获取仍然是一个挑战.
- 许多被诊断出来的患者失去了随访,阻碍了治疗和消除目标.
研究的目的:
- 评估邮寄邀请函和电话外展战略的有效性.
- 重新连接被诊断患有HCV但失去了医疗保健系统的患者.
- 为了促进及时的诊断确认和直接作用的抗病毒疗法.
主要方法:
- 对4816个抗HCV血清的审查,以确定677名失踪患者 (2010-2018).
- 邮寄邀请函发送给436名患者,随后多达三次电话给没有回复的患者.
- 受访者提供了加快的肝病学咨询和DAA治疗.
主要成果:
- 60%的接触患者 (260/436) 响应了检索策略.
- 47%的受访者 (119/260) 参与了后续护理.
- 66名患者开始DAA,达到100%的持续病毒学反应,占原始队列的10%.
结论:
- 双模式的检索策略有效地将失去的HCV患者重新连接到护理.
- 这种方法使得人们能够获得治疗性DAA治疗.
- 成功重新投入支持国家消除C型肝炎病毒的目标.
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