超重作为COVID-19严重性风险因素 - - 一项回顾性研究
Ana Beatriz Vasconcelos de Oliveira1, Denise Zaffari1, José Antonio Tesser Poloni1
1Universidade do Vale do Rio dos Sinos (UNISINOS).
Nutricion hospitalaria
|September 29, 2025
概括
肥胖症显著恶化COVID-19的预后,增加了重症监护室 (ICU) 的入院和死亡风险. 超重独立地提高了机械通风的需要,并延长了冠状病毒疾病2019患者的ICU停留时间.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
背景情况:
- 肥胖是巴西日益蔓延的流行病,与心血管疾病 (CVD),代谢障碍和严重感染有关.
- 新型冠状病毒疾病2019 (COVID-19) 在全球造成了数百万人的死亡.
- 了解肥胖等风险因素对于管理COVID-19结果至关重要.
研究的目的:
- 调查超重 (超重/肥胖) 与COVID-19患者的临床预后之间的关联.
- 确定超重是否会影响诸如重症监护室 (ICU) 住院,机械通风 (MV) 和死亡率等结果.
主要方法:
- 在巴西南部进行了一项纵向的回顾性队列研究.
- COVID-19患者被分为瘦身/肥胖和超重/肥胖组.
- 人口,临床,营养,生化和结果数据从医疗记录中收集.
主要成果:
- 大多数患者 (66.3%) 超重或肥胖.
- 与正常体重患者相比,超重患者的ICU访问次数更多.
- 超重,特别是在ICU入院时,增加了4.16倍的死亡风险,并与更长的ICU停留和增加机械通风 (MV) 需求有关.
结论:
- 集中治疗室入院是COVID-19患者死亡率的重要预测因素.
- 超重/肥胖的存在放大了ICU入院和死亡率之间的关联.
- 超重独立地预测了更长的ICU停留时间和更高的机械通风使用率.
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