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Updated: Jan 16, 2026

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在小脑神经发育过程中,多镇压复合体1和2独立且动态调节欧克罗马丁

Aditya Parmar1, Anjali Srinivasan1, Lena Krockenberger1

  • 1Department of Pathology, University of California San Diego, La Jolla, California, United States of America.

PLoS genetics
|September 29, 2025
PubMed
概括

多镇压复合体 (PRCs) 微调小鼠小脑发育中的基因调控. 通过PRC1沉积的H2AK119ub和通过PRC2沉积的H3K27me1对成熟大脑中的未结合活动产生影响,影响cis-regulatory元素和转录.

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