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Updated: Jan 16, 2026

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皮奥格利塔通过自和AMPK激活在缺乏α-1抗素的小鼠中减少肝脏α-1抗素的积累

Yuanqing Lu1, Regina Oshins2, Nesmine R Maptue3

  • 1Department of Neurosurgery, University of Florida, Gainesville, Florida, United States.

American journal of physiology. Gastrointestinal and liver physiology
|September 29, 2025
PubMed
概括

皮奥格利塔通过激活AMPK并促进自减少有害的Zα-1抗素 (ZAAT) 在肝细胞中的积累. 这为与α-1抗素缺乏 (AATD) 相关的肝病提供了潜在的新疗法.

关键词:
自自是自的过程.皮奥格利塔 (pioglitazone) 是一种药物.α-1 抗素缺乏症

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