乳制品摄入量和冠状动脉化:年轻成人冠状动脉风险发展 (心脏病) 前性队列研究
Ethan J Cannon1, David R Jacobs1, Lyn M Steffen1
1Division of Epidemiology & Community Health, University of Minnesota School of Public Health, Minneapolis, MN, United States.
The Journal of nutrition
|September 29, 2025
概括
年轻成人摄入全脂乳制品与冠状动脉化 (CAC) 的风险较低有关. 这些发现表明,目前的饮食建议可能需要重新评估,以预防心脏病.
科学领域:
- 心血管健康 心血管健康
- 营养流行病学 营养流行病学
- 动脉样硬化研究 动脉样硬化研究
背景情况:
- 在乳制品摄入量和冠状动脉疾病 (CAD) 方面存在不一致的发现.
- 在年轻成年期消费乳制品对冠状动脉化 (CAC) 的影响,这是动脉样硬化的早期指标,目前尚不清楚.
研究的目的:
- 检查乳制品摄入量与CAC存在之间的关联.
- 研究年轻成年人的乳制品消费模式及其对心血管的长期影响.
主要方法:
- 来自冠状动脉风险发展在年轻成年人 (CARDIA) 研究的3110名参与者的前性队列研究.
- 随访25年,通过饮食史评估乳制品摄入量,并在15年,20年和25年测量CAC.
- 考克斯比例危害回归分析,以评估CAC与各种乳制品摄入类别 (总量,全脂,低脂) 之间的关联.
主要成果:
- 较高的全脂乳制品摄入量显示,在对共变量进行调整后,与患有CAC的风险有相反的关联.
- 全脂乳制品和CAC风险之间的反向关联在进一步调整身体质量指数后被减弱.
- 在总乳制品,低脂乳制品或特定乳制品亚组和CAC之间没有发现统计学上显著的关联.
结论:
- 年轻人的全脂乳制品消费与未来的冠状动脉化相反相关.
- 目前的饮食建议强调低脂肪乳制品用于CAD预防,可能需要根据这些发现重新评估.
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