通过空间依赖性分析,探索年轻男性精液质量的地理差异
Rita Rahban1,2, Hugo-Alejandro Santa-Ramírez3, Alfred Senn1,2
1Swiss Centre for Applied Human Toxicology (SCAHT), University of Geneva, Geneva, Switzerland.
Human reproduction (Oxford, England)
|September 29, 2025
概括
在瑞士,精液质量不是随机的;空间分析显示出不同的热点和冷点. 土地使用等环境因素可能会影响男性生殖健康的这些地理模式.
科学领域:
- 生殖健康 生殖健康
- 环境流行病学环境流行病学
- 空间分析 空间分析
背景情况:
- 之前关于欧洲精液质量变化的研究表明环境影响,但缺乏国家一级的地理精度.
- 现有的研究往往集中在具有小样本规模的城市地区,在了解国家空间模式方面留下了差距.
研究的目的:
- 调查精液质量参数是否在整个瑞士表现出空间模式.
- 确定精液质量的潜在地理集群 (热点和冷点).
- 探索精液质量的空间变化与环境因素之间的关系.
主要方法:
- 对2677名在征兵期间 (2005-2018) 招募的瑞士男性 (18-22岁) 进行横截面研究.
- 收集了精液样本和生活方式问卷;使用当地的Getis-Ord Gi*统计 (25公里空间滞后) 分析了地理引用的居住数据.
- 在500米半径的住宅内,土地使用数据 (1992-1997,2004-2009) 已在已识别的集群之间进行了比较.
主要成果:
- 精液质量参数显示显著的空间聚类,而不是整个瑞士的随机分布.
- 在西瑞士中部地区发现了持续的冷点 (低值),料/田间作物的比例较高,建筑面积较低.
- 热点 (高值) 与冷点相比,建筑面积的比例明显高.
结论:
- 瑞士的精液质量参数表现出明显的空间聚类,暗示环境影响.
- 该研究开创了全国范围的精液质量分析空间依赖方法.
- 调查结果可以为针对性环境监测和生殖健康战略的公共卫生政策提供信息.
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