在患有重度抑郁症的患者中,饮食障碍症状和潜伏双极性之间的关联
Y V Yakovleva1, E D Kasyanov1, G V Rukavishnikov1
1Department of Social Neuropsychiatry, VM Bekhterev National Medical Research Center for Psychiatry and Neurology, Saint Petersburg, Russia.
概括
患有严重抑郁症 (MDD) 的饮食失调患者表现出更早的发病和更长的发作,这表明与双相情感障碍有联系. 这些发现强调了评估MDD患者的饮食行为对于更好的诊断和治疗的重要性.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 大型抑郁症 (MDD) 是一种常见的心理健康状况.
- 饮食障碍症状可能与MDD同时发生,但其临床相关性尚未完全理解.
研究的目的:
- 研究被诊断患有MDD的患者中饮食障碍症状与各种临床和心理特征之间的相关性.
- 确定与饮食失调行为相关的MDD的特定特征.
主要方法:
- 从七个俄罗斯中心招募了338名患者 (216名女性,122名男性) 的队列,年龄在18-59岁之间,患有MDD.
- 通过使用小型国际神经精神病学面试来确认诊断.
- 评估包括饮食态度测试 (EAT-26) 用于饮食失调,蒙哥马利-阿斯伯格抑郁症评分尺度用于抑郁症严重程度,抑郁症检查清单,哥伦比亚自杀严重程度评分尺度,医院焦虑和抑郁症尺度以及州道焦虑库存.
主要成果:
- 在EAT-26上获得更高的分数与最长的抑郁情节持续时间更长以及MDD发病年龄更早有关.
- 饮食失调与抑郁症期间的过食倾向有关.
- EAT-26得分与低躁狂症状,自杀念头和特征焦虑正相关.
结论:
- 患有MDD和明显的饮食失调行为的患者表现出更早的发病,更长的抑郁期,以及更高水平的躁狂症状.
- 这些临床标志物表明MDD和饮食失调的个体可能存在潜在的双极性或增加了发展为双极性障碍的风险.
- 这些发现强调需要评估MDD患者的饮食行为,以确定那些患双相情感障碍的风险较高的人.
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