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Updated: Jan 16, 2026

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一个基本的框架来解释在真核生物中拼接位置的选择

Craig I Dent1,2, Stefan Prodic1,3, Aiswarya Balakrishnan1,4

  • 1School of Biological Sciences, Monash University, Clayton Campus, Melbourne, VIC, Australia.

Nature communications
|September 29, 2025
PubMed
概括

遗传变异通过改变结合点强度,显著影响基因拼接. 这项研究量化了跨物种的拼接地点使用情况,揭示了 cis 作用变异作为主要驱动因素,并确定了六合体排名作为通用拼接规则.

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