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Updated: Jan 16, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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单细胞拼接的遗传决定因素是丰富的疾病易感位置

Isar Nassiri1,2,3,4,5, James J Gilchrist6,7, Orion Tong6

  • 1Oxford-GSK Institute of Molecular and Computational Medicine (IMCM), Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK. isar.nassiri@ndcn.ox.ac.uk.

Nature communications
|September 29, 2025
PubMed
概括

遗传变异会影响单细胞如何根据免疫细胞状态不同地结合基因. 这影响基因表达,并揭示了COVID-19和癌症等疾病的机制.

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