与慢性病的新发病相关的饮食模式使用集群算法
Dougho Park1,2, Jinmi Kim3, Da Woon Kim4
1Medical Science and Engineering, Graduate School of Convergence Science and Technology, Pohang University of Science and Technology, Pohang, South Korea.
Scientific reports
|September 29, 2025
概括
一种特定的饮食模式,总摄入量低但碳水化合物含量高,与韩国成年人患慢性病 (CKD) 的风险更高有关. 保持均衡,富含营养的饮食是预防CKD的关键,特别是在高危人群中.
科学领域:
- 营养科学 营养科学
- 流行病学 流行病学
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 饮食模式显著影响慢性病 (CKD) 的发展.
- 了解这些模式对于在不同人群中有效的CKD预防策略至关重要.
- 之前的研究强调,需要在特定种族群体内调查饮食-CKD关联.
研究的目的:
- 在韩国成年人中识别不同的饮食模式.
- 检查这些已识别的饮食模式与新发性CKD的发病率之间的联系.
- 根据饮食模式,探索潜在的高风险子组,以开发CKD.
主要方法:
- 使用韩国基因组和流行病学研究 (2004-2016) 的数据进行了回顾性队列研究.
- K-意味着对食物数量 (106种食物) 和营养素摄入量 (22种营养素) 进行集群分析,以确定饮食模式.
- 考克斯回归分析用于确定饮食集群与新发性CKD发展之间的关联.
主要成果:
- 在57,213名参与者中发现了三种不同的饮食模式.
- 集群C,以较低的整体食物/能量/营养摄入量和较高的碳水化合物摄入量为特征,显示出与增加CKD风险的独立关联 (aHR,1.59;95% CI,1.04-2.41).
- 与集群C相关的CKD风险增加在包括老年人 (≥65岁),男性,先前患有心血管疾病,静脉血压升高 (≥130 mmHg) 和肥胖 (BMI ≥25 kg/m2) 的子组中是一致的.
结论:
- 饮食摄入量的数量和质量都在韩国成年人中CKD的发展中起作用.
- 均衡,富含营养的饮食对于预防CKD至关重要,特别是在已确定的高风险人群中.
- 饮食模式分析为有针对性的公共卫生干预提供了宝贵的见解,并为预防CKD提供了个性化的营养指导.
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