血管内干预治疗后术后恶心和吐的危险因素:一个病例对照研究
Lilin Fan1, Mingyue Qiao1, Shiyi Qin1
1Department of Vascular and Endovascular Surgery, The First Affiliation Hospital (Southwest Hospital), Army Medical University, Gaotanyan Main Street 30, Shapingba District, Chongqing, 400038, China.
Scientific reports
|September 29, 2025
概括
女性性别,过敏,功能衰竭,栓塞和高剂量对比剂增加了内血管治疗后手术后恶心和吐 (PONV) 的风险. 识别这些因素有助于制定PONV预防战略.
科学领域:
- 医学研究 医学研究
- 临床干预是指临床干预.
- 患者安全 患者安全
背景情况:
- 手术后恶心和吐 (PONV) 是内血管手术后的常见并发症.
- 在接受监控麻醉护理 (MAC) 内血管治疗的患者中,PONV的风险因素尚不清楚.
研究的目的:
- 在接受内血管干预治疗的患者中识别和分析与PONV相关的风险因素.
- 描述有助于PONV发展的特定患者和程序元素.
主要方法:
- 一项涉及319名接受内血管治疗的患者的病例控制研究.
- 患有PONV (病例) 和没有PONV (对照) 的患者之间的临床和程序特征的比较.
- 多变量后勤回归分析以确定PONV的显著风险因素.
主要成果:
- 女性性别,过敏史,估计的淋巴细胞过率 (eGFR) <60毫升/分钟/1.73米2,栓塞程序和对比剂体积>400毫升被确定为显著的危险因素.
- 女性患者的风险高出2.66倍 (OR=2.66),过敏史高出6.56倍 (OR=6.56),功能衰竭高出5.89倍 (OR=5.89),栓塞高出3.29倍 (OR=3.29),高剂量对比剂高出18.54倍 (OR=18.54).
结论:
- 女性性别,过敏史,功能衰竭,栓塞和高对比剂体积是内血管干预后PONV的显著预测因素.
- 这些发现可以为接受内血管手术的高风险患者提供有针对性的PONV预防策略.
- 进一步的研究可能会探索在这个患者群体中将这些因素与PONV联系在一起的特定机制.
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