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在质瘤细胞中,SETD5 赋予了 TRAIL 阻力诱导

Lakshay Taneja1, Sachin Bhardwaj1, Ajay Kumar Yadav2

  • 1Molecular Cancer Genetics and Signal Transduction laboratory, Dr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, North Campus, Gate No. 1, Vishwavidyalaya Marg, Mall Road, 44, AH2, New Delhi, 110007, India.

Scientific reports
|September 29, 2025
PubMed
概括

在质母细胞瘤 (GBM) 中,SETD5 升级调节,促进对瘤坏死因子相关的亡诱导性联结体 (TRAIL) 治疗的耐药性. 抑制SETD5使GBM细胞对TRAIL敏感,提供了一个新的治疗策略.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.NFKBB 是一个非公开的银行.在SETD5中,SETD5是SETD5.轨道的轨道是一个轨道.

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