唾液激素分析作为评估骨成熟度的工具
Vaibhav Gandhi1, Sudha Gudhimella2, Gerard T Bradley2
1Department of Growth and Development, University of Nebraska Medical Center, 4000 East Campus Loop South, Lincoln, NE, 68583, USA. drvaibhavgandhi88@gmail.com.
Scientific reports
|September 29, 2025
概括
唾液生长激素 (GH) 水平在年轻女性 (10-11) 和男性 (13-14) 中达到峰值,为正牙患者评估骨成熟提供了一种非侵入性方法.
科学领域:
- 内分泌学 在内分泌学.
- 矯正牙科 矯正牙科是一種矯正牙科.
- 增长和发展 增长和发展
背景情况:
- 有限的研究存在于唾液激素水平和面骨生长.
- 已经确定了对骨成熟的荷尔蒙影响,但唾液分析尚未得到充分研究.
研究的目的:
- 在正牙患者中评估生长激素 (GH),皮质醇,和17β-雌激素的唾液水平.
- 研究这些唾液激素与面骨生长指标之间的相关性.
主要方法:
- 80名正牙患者 (40名男性,40名女性) 的横截面队列研究.
- 收集的唾液样本用于对GH,皮质醇,和17β-雌激素的ELISA分析.
- 用于第三指中 (MP3) 和椎脊椎成熟度指标 (CVMI) 阶段测定的侧向脑图.
主要成果:
- 唾液GH在10-11岁的女性和13-14岁的男性中达到峰值.
- 水平在两性中显示出相似的趋势,直到13岁,之后男性呈现出更高的水平.
- 青春期前的女性 (10-12岁) 显示了特定的MP3和CVMI阶段.
结论:
- 唾液GH水平可以作为一个非侵入性生物标志物,用于骨成熟度的评估在正牙科.
- 唾液中的荷尔蒙特征显示出预测面生长的潜力.
- 进一步的研究可以验证唾液激素分析用于增长预测.
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