阻塞性睡眠呼吸暂停的成年人中自杀倾向:系统性审查和元分析
Lauren R McCray1,2, Anna J Kulangara1, Shaun A Nguyen1
1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC, 29425, USA.
Sleep & breathing = Schlaf & Atmung
|September 29, 2025
概括
阻塞性睡眠呼吸暂停 (OSA) 与自杀思想和企图的风险增加有关. 医疗保健提供者应对OSA患者进行自杀倾向的查.
科学领域:
- 医学研究 医学研究
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种常见的疾病,与各种健康问题有关.
- 自杀,包括自杀念头,自杀企图和自杀死亡,是严重的公共卫生问题.
- 需要进一步研究OSA和自杀倾向之间的关系.
研究的目的:
- 评估阻塞性睡眠呼吸暂停 (OSA) 和自杀倾向之间的关联.
- 量化自杀念头,自杀企图和成年OSA患者自杀死亡的患病率和风险.
主要方法:
- 在多个数据库 (CINAHL,Cochrane Library,PubMed,PsycINFO,SCOPUS) 中进行了全面的文献搜索.
- 包括涉及成年OSA患者和自杀性结果的观察性研究;病例报告和中央睡眠呼吸暂停研究被排除在外.
- 进行了随机效应元分析,以综合有关流行率和相对风险的数据.
主要成果:
- 分析了15项涉及140多万参与者的研究.
- 与对照组相比,患有OSA患者的自杀念头 (12.4%与3.7%),自杀未遂 (1.5%与0.9%) 和自杀死亡 (0.3%与0.2%) 的患病率显著更高.
- 自杀念头的风险 (RR=1.8) 和自杀死亡的风险 (RR=1.9) 在OSA组显著更高.
结论:
- 自杀念头影响大约12%的OSA患者,近2%的人试图自杀.
- 在OSA和增加自杀倾向风险之间存在显著的关联.
- 耳鼻喉科医生和其他临床医生应主动评估和管理被诊断患有OSA的患者的自杀风险.
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