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Updated: Jan 16, 2026

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通过基于结构的虚拟查发现的小分子TLR4激动剂的辅助活性

Mohammad Kadivella1,2, Vivek P Varma1, Jusail Cp1,2

  • 1Laboratory of Vaccine Immunology, National Institute of Animal Biotechnology, Hyderabad, India.

Communications biology
|September 30, 2025
PubMed
概括

确定了新的合成小分子托尔类受体4 (TLR4) 激动剂NSF-951,NSF-418和NSF-501. NSF-951作为一种强大的TLR4激动剂,增强疫苗反应,而NSF-418和NSF-501是对抗剂.

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