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Updated: Jan 16, 2026

A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo
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CCR4+记忆Tregs和PD-1+T细胞作为活性结核病的新型免疫诊断生物标志物

Qiang Zhang1,2, Yifan Zhang1, Zhenpeng Guo1

  • 1Department of Epidemiology, Key Laboratory of Public Health Safety and Emergency Prevention and Control Technology of Higher Education Institutions in Jiangsu Province, Center for Global Health, School of Public Health, Nanjing Medical University, 101 Longmian Ave, Nanjing, 211166, China.

BMC infectious diseases
|September 30, 2025
PubMed
概括

结核病 (TB) 感染改变T细胞子集,具有特定的T细胞类型,如CCR4+记忆Tregs,CD4+PD-1+T细胞和CD8+PD-1+T细胞,具有预测活性TB (ATB) 的潜力. 这些发现为ATB诊断提供了新的生物标志物.

关键词:
有活性的结核病.疾病严重程度 疾病严重程度功能标记是指功能标记.免疫调节 免疫调节T细胞子集是T细胞的子集.

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