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Updated: Jul 14, 2026

Targeted DNA Methylation Analysis by Next-generation Sequencing
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Published on: February 24, 2015

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准确的DNA甲基化预测对C9orf72在致病范围的重复扩张等位基因

Naren Ramesh1, Alexandria Evans1, Kevin Wojta1

  • 1Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA.

HGG advances
|September 30, 2025
PubMed
概括

一个新的DNA甲基化 (DNAm) 预测器准确地识别了C9orf72重复扩张的载体,这是前性痴呆和ALS的常见原因. 这种表观遗传生物标志物在不同队列中显示出高准确性和概括性.

关键词:
C9orf7272 是一个很好的方法.通过DNA甲基化.预测器 预测器 预测器重复扩张的扩张.

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