儿科的炎症性肠病:应对旧的挑战和新兴的边界
Mohammed Al-Beltagi1,2, Nermin K Saeed3,4, Prabu Kumar Chokkalingam Mani5,6
1Department of Pediatrics, Faculty of Medicine, Tanta University, Tanta 31511, Algharbia, Egypt.
World journal of gastroenterology
|September 30, 2025
概括
儿童炎症性肠病 (IBD) 在全球范围内正在上升,对儿童构成独特的挑战. 精准医学和微生物组疗法的进步为改善诊断和治疗提供了新的希望.
科学领域:
- 胃肠病学和肝病学
- 儿科医学 儿科医学
- 免疫学 免疫学 免疫学
背景情况:
- 儿童炎症性肠病 (IBD),包括克罗恩氏病和性结肠炎,在全球范围内越来越普遍.
- 与成年人相比,儿童往往表现出更严重和更广泛的疾病,这带来了不同的临床挑战.
- 环境和遗传因素是导致儿科IBD发病率上升的关键因素,特别是在工业化国家.
研究的目的:
- 综合当前关于儿科IBD的知识,涵盖流行病学,诊断和管理.
- 探索儿科IBD护理的新兴前沿,包括精准医学和微生物组向治疗.
- 要突出独特的挑战和不断发展的策略来管理儿童的IBD.
主要方法:
- 全球和区域流行病学数据的叙述综合.
- 对临床分类,诊断进展和管理方法的审查.
- 强调精准医学,微生物组疗法和多学科护理方面的创新.
主要成果:
- 儿童IBD发病率在全球范围内不断增加,与环境和遗传相互作用有关.
- 新型诊断工具,年龄特定的治疗方法,生物药物和营养策略正在改变护理.
- 专注于非常早期的IBD,过渡期护理和政策调整反映了儿科IBD管理的复杂性.
结论:
- 儿科IBD的护理环境正在迅速发展,需要以儿童为中心的方法.
- 解决不同的病理生理学和发育影响对于有效的管理至关重要.
- 对遗传学,免疫路径和微生物组的持续研究对于个性化治疗和更好的全球结果至关重要.
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