对预测克罗恩病术后内镜复发的病理发现的评估:一项回顾性队列研究
Işıl Karabulut1, Erdinç Çetinkaya2,3, Nesrin Turhan4
1Department of Surgery, Ankara Bilkent City Hospital, Ankara 06800, Türkiye.
World journal of gastrointestinal surgery
|September 30, 2025
概括
在克罗恩病 (CD) 手术样本中,微观发现,如中性友性隐藏炎和隐藏,预测内镜复发. 建议对高风险的CD患者进行早期干预.
科学领域:
- 胃肠病学 胃肠病学
- 手术病理学手术病理学
- 炎症性肠道疾病研究研究
背景情况:
- 克罗恩氏病 (CD) 管理通常需要手术治疗医疗耐药病例.
- 手术后复发是CD患者的主要临床挑战.
- 鲁特吉茨评分是评估术后内镜复发的标准工具.
研究的目的:
- 调查切除肠道组织中的病理特征与鲁特吉尔茨评分之间的相关性.
- 确定微观和宏观发现对CD内镜复发的预测价值.
主要方法:
- 对32名接受手术的肠道CD患者的回顾性分析.
- 手术样本的组织病理学重新检查.
- 使用鲁特格尔茨分数对术后内镜发现的分类.
主要成果:
- 宏观发现与鲁特吉尔茨得分或复发率没有显著的相关性 (P > 0.05).
- 中性性隐藏炎 (P=0.035) 和隐藏 (P=0.010) 与较高的鲁特吉茨得分有显著的关联.
- 显微镜发现的炎症与内镜复发风险增加相关.
结论:
- 在切除的标本中存在中性友性密室炎和密室,表明CD复发的风险更高.
- 建议早期术后医学治疗和密切的内镜监测高风险的CD患者.
- 强调多学科的团队方法在CD复发管理中的治疗决策.
更多相关视频
15:49Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
32.5K
09:50Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice
Published on: February 11, 2019
10.2K
相关概念视频
01:21Inflammatory Bowel Disease V: Surgical Management
451
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
451
01:30Inflammatory Bowel Disease II: Crohn's Disease
960
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
960
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
568
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
568