手术后增强恢复对腹腔镜胃癌手术期间术后肠功能和肠菌群的影响
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Updated: Jan 16, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Xiao-Jie Lin1, Jia-Ze Xu2, Qiang Hu3
1Department of Mammography, Vascular Surgery, Hepatobiliary and Pancreatic Surgery, Zhejiang Tongde Hospital, Hangzhou 310000, Zhejiang Province, China.
手术后增强恢复 (ERAS) 协议显著改善胃肠功能恢复,并保持肠道微生物群的多样性,在接受腹腔镜胃癌手术的患者. 这些发现支持ERAS以获得更好的外科手术结果.
科学领域:
- 胃肠道学和外科瘤学
- 微生物组研究 微生物组研究
- 在外科手术期间的医学.
背景情况:
- 手术后增强恢复 (ERAS) 协议在术后护理中越来越多地被采用.
- 在胃癌手术后,ERAS对胃肠道恢复和肠道微生物群的影响需要进一步研究.
研究的目的:
- 评估ERAS协议在增强术后胃肠功能恢复方面的有效性.
- 评估ERAS在腹腔镜胃癌手术后对肠道微生物群组成的影响.
- 确定与改善临床结果和保持微生物多样性相关的因素.
主要方法:
- 对80名接受腹腔镜D2胃切除术的患者进行了回顾性分析.
- 在ERAS协议组 (n=40) 和传统护理组 (n=40) 之间的比较.
- 使用16S rRNA测序评估胃肠功能恢复,并发症和肠道微生物群.
主要成果:
- 在ERAS患者中,肠道功能的恢复显著加快,包括肠道声音的更早回归,第一次浮和排便 (P<0.05).
- 在ERAS和传统护理组之间,并发症率是可比的.
- 在术后,ERAS组显示了微生物多样性和益生菌群体的更好保存 (P < 0.05).
结论:
- 在腹腔镜胃癌手术后,ERAS协议对胃肠道恢复和肠道微生物群弹性产生积极影响.
- 通过早期养和较短的抗生素疗程来定制ERAS可能会增加益处,特别是对于年轻的患者.
- 需要进一步的研究来优化ERAS协议,以保护微生物群.
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