相关实验视频
Updated: Jan 16, 2026
08:39
A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
2.0K
维生素D和肌肉功能在多样化血液透析队列中的作用
Sara Mahdavi1,2,3, Katie Rosychuk2, Hulya Taskapan3
1Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Canadian journal of kidney health and disease
|September 30, 2025
概括
维生素D缺乏和缺乏补充与血液透析患者肌肉强度降低有关. 在这种人群中,较高的维生素D水平可能会改善肌肉骨功能.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 血液透析患者经常出现肌肉疲软和维生素D缺乏.
- 在这个群体中,维生素D状态,补充剂和肌肉力量之间的关系尚未完全理解.
研究的目的:
- 研究血清25-基维生素D (25(OH) D水平,维生素D摄入量,补充剂和血液透析患者的肌肉力量之间的关联.
- 评估维生素D缺乏和补充对这一群体肌肉功能的影响.
主要方法:
- 一项涉及多伦多81名成年血液透析患者的横截面研究.
- 使用数字动力计测量手握强度.
- 血清25(OH) D水平量化;通过食品日志评估饮食和补充剂摄入量.
- 多变量回归分析根据年龄,性别和干重量进行调整.
主要成果:
- 25%的参与者缺乏维生素D,47%的参与者手握力较弱.
- 较高的血清25(OH) D度和维生素D补充剂与手握强度有积极联系.
- 维生素D缺乏会使握力较弱的几率增加五倍以上.
- 饮食维生素D摄入量在大多数人中不足,但与力量没有独立相关.
结论:
- 维生素D缺乏和缺乏补充与血液透析患者肌肉强度降低相关.
- 保持足够的血清25 ((OH) D水平可能对支持这一群体的肌肉骨健康至关重要.
- 进一步的研究可以探索改善血液透析患者维生素D状态和肌肉功能的干预措施.
更多相关视频
06:47Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
9.8K
10:46A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
11.0K
相关概念视频
01:28Chronic Kidney Disease III: Interprofessional Care
344
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
344
01:23Role of Skin in Vitamin D Synthesis
7.6K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
7.6K
01:25Role of Vitamins in Maintaining Bone Health
5.0K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
5.0K
01:24Hemodialysis II: Procedure and Complications
648
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
648
01:25Hemodialysis I: Introduction
1.4K
Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
1.4K
01:25Hemodialysis III: Nursing Management
748
The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this...
748