对肢体缺血的外周内血管干预的基于性别的辐射暴露和临床结果:一项前性研究
Subrata Kar1, Clifton Espinoza2
1Division of Cardiology, Texas Tech University Health Sciences Center, Paul L. Foster School of Medicine, El Paso, TX 79905, United States. skar762@aim.com.
World journal of cardiology
|September 30, 2025
概括
接受外周内血管干预 (PEVI) 的男性有更高的辐射剂量区域产物 (DAP),但与女性相比,并发症率相似. 尽管辐射暴露的差异,PEVI对所有性别都是安全的.
科学领域:
- 血管外科 血管外科
- 干预性放射学 干预性放射学
- 辐射瘤学 辐射瘤学
背景情况:
- 外周内血管干预 (PEVI) 使用辐射,对患者和医疗保健专业人员构成健康风险.
- 了解性别特异性辐射暴露对于优化PEVI安全协议至关重要.
研究的目的:
- 调查PEVI期间辐射暴露的潜在性别差异.
- 为了比较经过PEVI的男性和女性之间的手术结果和并发症率.
主要方法:
- 一项前性观察性研究包括186名接受PEVI治疗的患者.
- 收集的数据包括辐射指标 (空气基马,剂量区域产物[DAP]),光镜时间,对比度使用和临床结果.
- 患者按性别分层:女性 (n=99) 和男性 (n=87).
主要成果:
- 与女性相比,男性的剂量区域产品 (DAP) 显著更高 (P=0.047).
- 两性之间在空气克尔马,光镜时间,对比度使用或二次终点 (死亡率,MACE,并发症) 上没有发现显著差异.
- 随访时间平均为3.9个月.
结论:
- 在PEVI期间,男性在暴露区域吸收更多的辐射,正如较高的DAP所示.
- 尽管辐射有差异,但PEVI在男性和女性的安全性和结果相似.
- 这些发现支持PEVI跨性别安全应用.
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