结肠瘤和腹腔炎:一个系统的审查
1Department of Medicine, Faculty of Medicine, Umm AL-Qura University, Makkah 8156-24381, Saudi Arabia. ymkhayyat@uqu.edu.sa.
World journal of gastroenterology
|September 30, 2025
概括
病患者的结直肠癌 (CRC) 风险略有增加. 早期查和意识对于及时诊断和改善这一群体的结果至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
背景情况:
- 乳病 (CD) 是一种与遗传倾向相关的慢性炎症状况.
- 质暴露会触发小肠以外的免疫反应,可能导致结肠直肠癌 (CRC) 的发展.
- 虽然在CD中识别了小肠恶性瘤,但由于有限的下肠道查,CRC往往被诊断不足.
研究的目的:
- 综合关于CD-CRC关联的证据.
- 在CD患者中通过下肠道查提倡早期CRC检测.
- 为患有CRC风险的CD患者提出个性化的治疗策略.
主要方法:
- 对Scopus,科学网和PubMed数据库的系统文献审查.
- 关键词集中在乳病,结肠癌和瘤.
- 对病理生理机制,临床表现和结果的分析.
主要成果:
- 在审查了3028个引用之后,包括了136项研究.
- 确定了CD和CRC之间的显著关联,影响了患者的存活率.
- 根据这些发现,建议进行早期查和干预.
结论:
- 在CD患者中观察到结肠淋巴瘤和腺癌的发病率较低.
- 在CD患者中,CRC通常呈现为非特异性和晚期.
- 在CD患者中增加的CRC风险与诸如质暴露时间和饮食遵守等因素有关.
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