表面增强拉曼散射 (SERS) 用于检测草药配方中的活性成分 piperine
G R Advaya1, Gaurav Banerjee1, Jobin Cyriac1
1Department of Chemistry, Indian Institute of Space Science and Technology, Thiruvananthapuram, Kerala, 695 547, INDIA. jobincyriac@iist.ac.in.
Analytical methods : advancing methods and applications
|September 30, 2025
概括
表面增强拉曼散射 (SERS) 提供了一种使用Ag@citrate纳米粒子检测piperine的敏感方法. 这种技术为药品提供了快速的质量控制和真实性验证.
科学领域:
- 分析化学 分析化学
- 频谱学是一种光谱学.
- 纳米技术纳米技术
背景情况:
- 黑胡中的关键类化合物皮佩林 (Piperine) 对于质量控制至关重要.
- 精确检测皮佩林对于药品认证至关重要.
- 现有的方法可能缺乏快速分析所需的灵敏度或速度.
研究的目的:
- 开发和演示一种表面增强的拉曼散射 (SERS) 方法来检测皮佩林.
- 为了利用Ag@酸盐纳米粒子作为SERS分析的有效基质.
- 验证SERS方法用于药品质量保证.
主要方法:
- 使用Ag@酸盐纳米颗粒作为表面增强拉曼散射 (SERS) 的基质.
- 采用经济的拉曼光谱仪与便携式探针用于管道分析.
- 根据特征的拉曼峰和信号放大,确定和量化了皮佩林.
主要成果:
- 使用Ag@酸盐纳米颗粒实现了大量的piperine信号放大.
- 在 piperine 检测中表现出高灵敏度,可重复性和特异性.
- 成功分析了商业阿育吠陀药物 (Thaleesapathradi choornam和Ashta choornam) 中的皮佩林含量.
结论:
- 使用Ag@酸盐纳米颗粒的SERS是一种高度有效和敏感的方法来检测piperine.
- 开发的SERS方法为药品质量保证提供了一个快速可靠的工具.
- 这种技术在制药行业的认证和质量控制方面具有重大潜力.
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