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Updated: Jan 16, 2026

Designing, Packaging, and Delivery of High Titer CRISPR Retro and Lentiviruses via Stereotaxic Injection
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Designing, Packaging, and Delivery of High Titer CRISPR Retro and Lentiviruses via Stereotaxic Injection

Published on: May 23, 2016

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基于CRISPR的高效基因组编辑用于可诱导的降解系统,以实现对大型双链DNA病毒基因组中蛋白质功能的时间控制

Kihye Shin1,2, Eui Tae Kim1,2

  • 1Department of Microbiology and Immunology, Jeju National University College of Medicine, Jeju 63241, Republic of Korea.

Journal of microbiology (Seoul, Korea)
|September 30, 2025
PubMed
概括

我们开发了一种优化的CRISPR-Cas9系统,用于精确地基因改造人类细胞巨核病毒 (HCMV). 这种工具可以有效地标记和功能分析重要的病毒基因,推动HCMV研究.

关键词:
通过CRISPR-Cas9进行基因组编辑.辅酶诱导性降解 (AID) 系统人类细胞巨型病毒 (HCMV)整合酶缺乏的晶体病毒 (IDLV)

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