在诊断上部内镜检查后疑似传染性发烧的危险因素:在韩国的一项回顾性研究中,普罗波过量服用
Sunmin Lee1, Jung-Hwan Lee2,3, Jongbeom Shin2
1College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon, Korea.
Clinical endoscopy
|September 30, 2025
概括
在上部内镜检查期间服用过多的普罗波会增加疑似后内镜传染性发烧 (SPIF) 的风险. 谨慎镇静至关重要,特别是对于痴呆症或漫长手术的患者来说,以防止发烧和肺炎等并发症.
科学领域:
- 胃肠病学 胃肠病学
- 麻醉学 麻醉学
- 传染性疾病 传染性疾病
背景情况:
- 普罗波是用于上部内镜的常见镇静剂.
- 过量服用普罗波可能会导致诸如吸入性肺炎等并发症.
- 醇过量服用与疑似后内镜传染性发烧 (SPIF) 之间的联系需要进行调查.
研究的目的:
- 为了调查是否普罗波过量服用是上部内镜检查后SPIF的危险因素.
- 确定SPIF的其他潜在风险因素.
主要方法:
- 对1474名接受上部内镜检查的患者进行了回顾性分析.
- SPIF定义为新发烧 (≥38°C) 在内镜检查后三天内出现,具有特定的临床或实验室标记.
- 评估的风险因素包括并发症,镇静剂剂量,手术持续时间和内镜医生的经验.
主要成果:
- 新发烧发生在3.7%的患者中;1.9%符合SPIF标准.
- 醇过量服用 (>2.2 mg/kg) 显著增加了新发烧 (OR,1.03) 和SPIF (OR,1.04) 的风险.
- 痴呆症和长时间的手术 (>5分钟) 也被确定为SPIF的危险因素.
结论:
- 醇过量服用是SPIF的重要危险因素.
- 合理的镇静管理对于减轻SPIF风险至关重要.
- 痴呆症患者和接受长期手术的患者需要高度警.
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