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Updated: Jun 27, 2026

High Throughput Quantitative Expression Screening and Purification Applied to Recombinant Disulfide-rich Venom Proteins Produced in E. coli
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对多克隆抗体开发的石毒素β子单元的生物信息分析和重组表达

Mohammadreza Rahmani1, Shahram Nazarian1, Hossein Samiei-Abianeh1,2

  • 1Department of Biology, Faculty of Basic Sciences, Imam Hossein University, Tehran, Iran.

Iranian journal of immunology : IJI
|September 30, 2025
PubMed
概括

研究人员创造了一个重组石鱼 (Synanceia spp.). 毒素亚单元,并产生了强大的抗体. 这一进步表明,有望创造有效的抗毒剂来抵抗石鱼刺痛.

关键词:
抗毒药是一种抗毒药.鱼有毒的鱼有毒的鱼有毒的这是一种多克隆抗血清.再组合蛋白质是一种重组蛋白质.石头毒素是一种毒素.

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Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...