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Updated: Jan 16, 2026

Monitoring Conformational Dynamics of Single Unmodified Proteins using Plasmonic Nanotweezers
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Monitoring Conformational Dynamics of Single Unmodified Proteins using Plasmonic Nanotweezers

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通过反向等离子共振能量转移来长期监测单个器官水平的酶活性

Dengyun Lu1,2, He Wang1, Yang Shi1

  • 1Guangdong Provincial Key Laboratory of Nanophotonic Manipulation, Institute of Nanophotonics, College of Physics & Optoelectronic Engineering, Jinan University, Guangzhou 511443, P. R. China.

ACS nano
|September 30, 2025
PubMed
概括

这项研究引入了一种新的光学技术,使用反向等离子共振能量转移 (rPRET) 纳米天线来实时监测单个有机体内的依赖氧的酶活性,揭示细胞类型之间的代谢差异.

关键词:
酶活性的酶活性.器官间的相互作用分子成像分子成像技术纳米塑料的使用反向等离子体共振能量转移的能量转移.

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相关概念视频

Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...
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