增材制造的微板用于同时测定色度和电化学检测阿特罗宾
Larissa M A Melo1,2, Elena Bernalte1, Robert D Crapnell1
1Faculty of Science and Engineering, Manchester Metropolitan University, Dalton Building, Chester Street, M1 5GD, Great Britain. c.banks@mmu.ac.uk.
The Analyst
|September 30, 2025
概括
一个新的双电化学和色度传感器,3D打印在一个步骤,使得快速的氨酸 (ATP) 检测. 这个高效的平台为法医应用提供了实用,定量分析.
科学领域:
- 分析化学 分析化学
- 材料科学 材料科学 材料科学
- 法医科学 法医科学 法医科学
背景情况:
- 开发用于快速检测分析物的综合传感平台.
- 在法医调查中需要有效和实用的分析工具.
- 在复杂的样本矩阵中单模传感技术的局限性.
研究的目的:
- 开发一种新的,单步3D打印的双模式 (电化学和色度) 传感平台.
- 使用该平台检测氨酸 (ATP).
- 为了证明平台的效率,实用性和适合法医分析.
主要方法:
- 增材制造 (3D打印) 创建一个96井板兼容的传感器.
- 集成一个导电性的聚烯盘电极和透明的聚烯墙壁.
- 双模式检测涉及色度反应与绿色和方波电压测量.
主要成果:
- 成功开发了一种单打印双模式传感器.
- 广泛的线性范围用于检测阿特罗宾 (0.6520.83毫克毫升-1和5.2120.83毫克毫升-1).
- 低检测和量化极限 (0.15毫克毫升-1和0.50毫克毫升-1).
- 在添加饮料和生物样本中,回收率高 (接近100%),表明没有矩阵效应.
结论:
- 3D打印的双模式传感器提供了一种高效和实用的方法来检测氨酸.
- 增材制造和多模式传感之间的协同作用为法医应用提供了一个强大的平台.
- 开发的方法表现出高灵敏度,准确性和适用于现实世界样本的可用性.
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