美国女性治疗尿路感染的住院患者死亡率 2016-2020年
Gabriella Rustia1, Megan Abrams2, Stephen Rhodes3
1Division of Female Pelvic Medicine and Reconstructive Surgery, Urology Institute, University Hospitals, Cleveland, OH.
Urogynecology (Philadelphia, Pa.)
|September 30, 2025
概括
女性因尿路感染 (UTI) 住院治疗很少导致死亡,即使是老年患者. 晚年和某些疾病 (如转移性癌症) 会增加死亡风险,而其他疾病 (如细菌病) 会降低死亡风险.
科学领域:
- 传染性疾病 传染性疾病
- 老年医学 老年医学
- 流行病学 流行病学
背景情况:
- 尿路感染 (UTI) 在成年女性中很常见,经常由妇科医生和泌尿科医生治疗.
- 了解住院尿路感染患者的死亡风险因素对于临床管理和公共卫生策略至关重要.
研究的目的:
- 确定患有尿路感染的初级诊断的住院妇女死亡率的频率和相关因素.
- 确定影响尿路感染在医院死亡率的人口统计学,并发病和诊断因素.
主要方法:
- 从2016年至2020年使用国家住院患者样本 (NIS) 进行回顾性队列研究.
- 包括初级尿路感染诊断的成年女性,分析人口统计数据,并发症和使用ICD-10代码的诊断.
- 采用多变量逻辑回归来确定住院死亡率的独立预测因素.
主要成果:
- 总共有330,905例因尿路感染住院的病例被分析,整体死亡率为0.48% (1,588例死亡).
- 随着年龄的增长,死亡风险显著增加,特别是在85岁以上的人群中 (aOR 8.37).
- 转移性癌症 (aOR 4.25),肺炎 (aOR 3.68) 和体重减轻 (aOR 2.98) 与增加的死亡率有很强的关联,而细菌病 (aOR 0.65) 和复杂的高血压 (aOR 0.61) 与降低的死亡率有关.
结论:
- 与初级尿路感染诊断相关的住院死亡很少发生,即使在重症和老年妇女中也是如此.
- 年龄和特定的并发症是住院尿路感染患者死亡率的重要预测因素.
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