在正常压力中性别差异 脑水症诊断和尿路结果
Nishanth S Sadagopan1, Rishi Jain1, Rahul K Chaliparambil1
1Departments of Neurological Surgery.
Urogynecology (Philadelphia, Pa.)
|September 30, 2025
概括
患有尿失禁 (UI) 的女性经历了异常性正常压力头症 (iNPH) 的延迟诊断. 早期诊断和治疗对于iNPH患者的更好的结果至关重要.
科学领域:
- 神经学 神经学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 老年病的医生 老年病的医生
背景情况:
- 异常性正常压力脑症 (iNPH) 与痴呆症,步态障碍和尿失禁 (UI) 相伴.
- 尿失禁在女性中经常被忽视,归因于正常的衰老,延迟了iNPH诊断.
- 这凸显了iNPH诊断和管理中的潜在基于性别的差异.
研究的目的:
- 调查从UI文档到iNPH诊断的时间中的基于性别的差异.
- 为了比较手术后的UI结果,在对iNPH进行心室外皮管突变安置后,两性之间.
主要方法:
- 对82名iNPH患者进行了回顾性,单中心的研究,这些患者具有完整的症状三元组.
- 主要结果:从UI文档到iNPH诊断的时间,按性别分析.
- 二次结局:经过手术后3个月的步态,认知和UI的改善,按性别分析.
主要成果:
- 与男性相比,女性对iNPH诊断的时间明显较长 (40.3个月与16.8个月).
- 手术后的步态,认知和UI在改善方面没有明显的性别差异.
- 女性的UI完全解决率较低 (13.6%与36.8%相比),诊断时间较短与女性的UI改善相关.
结论:
- 女性面临iNPH的诊断延迟和完全UI症状解消率较低.
- 在UI的妇女中提高对iNPH的临床意识对于及时查至关重要.
- 及时诊断和干预可能会改善iNPH患者,特别是女性的治疗结果.
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