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Updated: Jan 16, 2026

Microengineering 3D Collagen Hydrogels with Long-Range Fiber Alignment
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与矩阵相关的细胞外囊泡通过呈现原VI来调节人类光滑肌肉细胞的粘附和方向性

Alexander N Kapustin1, Sofia Serena Tsakali1, Meredith Whitehead1

  • 1School of Cardiovascular and Metabolic Medicine and Sciences, James Black Centre, King's College London, London, United Kingdom.

eLife
|September 30, 2025
PubMed
概括

纤维肌菌素 (FN) 触发血管光滑肌细胞 (VSMCs),释放细胞外囊泡 (sEVs),促进细胞入侵. 这些由FN刺激的sEV,富含原VI,驱动方向运动,对血管修复和动脉样硬化至关重要.

关键词:
细胞粘附 细胞粘附细胞生物学 细胞生物学细胞迁移 细胞迁移细胞外矩阵是细胞外矩阵.人类 人类 人类 人类 人类 人类 人类复兴再生是一种再生方式.

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