Tmax 10 体积与大核心中风中NWU Delta 独立相关
Vivek Yedavalli1, Hamza Adel Salim2,3,4, Dhairya A Lakhani5,6
1Department of Radiology, Division of Neuroradiology, Johns Hopkins Medical Center, Baltimore, MD, USA. vyedava1@jhmi.edu.
在急性缺血性中风 (AIS-LVO) 患者中,较大的严重低透组织体积 (Tmax > 10s) 预测大脑胀的增长. 这一发现有助于预测中风进展,并为治疗策略提供信息.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 生物医学成像技术 生物医学成像技术
背景情况:
- 预测大脑的生长对于急性缺血性中风至关重要,因为大血管封闭 (AIS-LVO) 具有大缺血核心.
- 需要可靠的成像生物标志物来评估低透组织体积.
研究的目的:
- 在AIS-LVO患者中,研究严重低透组织体积 (Tmax > 10s) 和净吸水量 (∆NWU) 进展之间的关联.
- 为了确定Tmax> 10s体积是否可以预测大核心中风中胀的增长.
主要方法:
- 对接受内血管治疗 (EVT) 的AIS-LVO患者进行了回顾性多中心队列研究.
- 从输液成像中分析Tmax > 10s体积和从非对比头部CT中分析∆NWU.
- 对临床和成像变量进行统计调整.
主要成果:
- 更高的Tmax>10s体积独立地与更大的∆NWU相关 (β = -0.34,P = 0.043).
- 较低的ASPECTS分数也独立地与较大的∆NWU相关 (β = -0.30,P = 0.035).
- 包括95名患者 (平均年龄74岁,55%为女性).
结论:
- 严重的治疗前低 perfusion,表示较大的Tmax> 10s体积,对于预测AIS-LVO中大脑胀的增长很重要.
- 这些发现可以为管理大核心中风的临床策略提供信息.
- 需要进一步的前性研究来验证.
更多相关视频
11:00Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section
Published on: July 19, 2016
07:52Author Spotlight: Advancing Human Brain Modulation – Optimized Protocols for Transcranial Ultrasound Stimulation Experiments
Published on: June 28, 2024
相关概念视频
Regulation of Stroke Volume
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Cardiac Output and Stroke Volume
In an average resting adult male, the typical cardiac...
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
General External Flow Characteristics
Urodynamic Studies: Uroflowmetry
Assessment of apical radial pulse
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation
