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Updated: Jan 16, 2026

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
11:12

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

Published on: April 11, 2019

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患有人类先天免疫错误的成年患者的恶性和自身免疫敏感性

Alejandro Segura-Tudela1, Celia Nieto-López1,2, Francisco Javier Bermejo-Olivera1

  • 1Department of Immunology, University Hospital 12 de Octubre, Madrid, Spain.

Journal of clinical immunology
|September 30, 2025
PubMed
概括

具有分子诊断的免疫缺陷 (IEI) 患者表现出更多恶性瘤,特别是血液类型. 没有分子诊断的患者有更多的固体瘤,这凸显了对管理IEI并发症的遗传洞察的重要性.

关键词:
这是一个类似于ALPS的系统.自免疫淋巴增殖综合征 (ALPS)免疫系统的调节失调.杰弗里模型基金会 (JMF) 警告标志淋巴细胞的扩散.主要免疫调节障碍 (PIRD)

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