自闭症中的本地和全球视觉处理:神经成像研究的系统审查和元分析
Yating Huang1, Hjalmar Nobel Norrman2, Manuel Oliva2
1Center of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Centre for Psychiatry Research, Department of Women's and Children's Health, Karolinska Institutet Stockholm Health Care Services, Region Stockholm, 11364, Stockholm, Sweden. yating.huang@ki.se.
Journal of autism and developmental disorders
|September 30, 2025
概括
与对照人群相比,自闭症患者在视觉处理任务中表现出不同的大脑激活模式. 这项研究揭示了视觉皮层和表皮区域参与的差异,突出了自闭症谱状况 (ASC) 中独特的神经机制.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 发展心理学 发展心理学
背景情况:
- 自闭症谱状况 (ASC) 与非典型的视觉处理有关,影响了本地和全球视觉信息.
- 以前的研究表明,ASC患者在各种视觉任务中大脑激活的差异.
- 还需要对ASC中面向细节的视觉注意力的神经基础进行详细的理解.
研究的目的:
- 系统地审查和对ASC患者的局部和全球视觉处理的脑成像研究进行元分析.
- 在视觉任务期间,调查ASC和神经类型控制 (CON) 个体之间大脑激活的差异.
- 为了澄清ASC中以细节为导向的视觉注意力背后的神经机制.
主要方法:
- 进行了系统审查和激活概率估计 (ALE) 的元分析.
- 包括15项研究,包括252名ASC患者和263名CON患者.
- 分析了专注于局部视觉处理 (细节) 和全球视觉处理 (配置) 的任务.
主要成果:
- 与CON相比,在ASC患者中观察到右下回 (BA 19) 的激活更大.
- 在小组内分析显示,ASC组的甲lamus和中椎 (BA 19) 的激活.
- 控制组显示在下顶叶片 (BA 40) 中的激活.
结论:
- 这些发现支持ASC中改变局部和全球视觉处理的理论.
- 自闭症患者可能更多地利用视觉皮质进行视觉处理任务.
- 神经类型的个体可能更多地依赖于视觉处理的头顶区域.
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