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Updated: Jan 16, 2026

Nanomechanics of Drug-target Interactions and Antibacterial Resistance Detection
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刚性与活性:基于分子工程的基因对抗多药耐药细菌的格拉米西丁S类别的设计

Mikołaj Śleziak1, Jarosław J Panek1, Tomasz Janek2

  • 1University of Wrocław, Faculty of Chemistry, F. Joliot-Curie St. 14, Wrocław 50-383, Poland.

Journal of medicinal chemistry
|September 30, 2025
PubMed
概括

研究人员探索了结构刚性如何影响抗微生物 (AMP). 他们发现,较不严格的AMP显示出更好的安全性和更广泛的抗细菌有效性,提供了新的治疗设计策略.

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