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Updated: Jan 16, 2026

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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CTLA-4封锁会使B细胞的表现转向自身免疫

Elif Çakan1, Meng Wang2, Yile Dai1

  • 1Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.

The Journal of clinical investigation
|September 30, 2025
PubMed
概括

检查点抑制剂,如抗CTLA-4,但不是抗PD-1,增加自身反应性B细胞,可能导致与免疫相关的不良事件 (irAEs) 和扩大抗瘤反应.

关键词:
这是一种自身免疫力.癌症免疫疗法癌症免疫疗法糖尿病 糖尿病 糖尿病免疫学 免疫学 免疫学宽容是一种宽容.

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