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Author Spotlight: Advanced Single-Molecule Techniques for Investigating Telomeric Protein-DNA Interactions
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端粒通过非端粒TRF2控制人类端粒酶 (TERT) 表达

Antara Sengupta1,2,3, Soujanya Vinayagamurthy1,2,3, Dristhi Soni1,2,3

  • 1Integrative and Functional Biology Unit, CSIR-Institute of Genomics and Integrative Biology, Delhi, India.

eLife
|September 30, 2025
PubMed
概括

端粒长度 (TL) 影响人类端粒酶逆转录酶 (TERT) 基因表达. 较短的端粒通过TRF2结合和PRC2招募增加TERT转录,而较长的端粒减少它,影响衰老和癌症.

关键词:
在 TRF2 中,TRF2 是 TRF2.癌症 癌症 癌症 癌症 癌症癌症生物学 癌症生物学染色体是一种染色体.表观遗传学是指表观遗传学.基因表达的基因表达方式人类 人类 人类 人类 人类 人类 人类端粒酶的使用方法端粒是什么意思 端粒是什么意思

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