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Updated: Jan 16, 2026

Author Spotlight: THP-1 Macrophage Response to LPS/ATP — Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum
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Author Spotlight: THP-1 Macrophage Response to LPS/ATP — Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum

Published on: May 3, 2024

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聚菲林I通过激活caspase-6/ZBP1/NLRP3信号通路,诱导扩散型大B细胞淋巴瘤中的热致死

Yulian Liu1, Mengyue Fan2, Yuanxin Chen2

  • 1Central laboratory, Linyi People's hospital, Linyi 276000, China; Key Laboratory for Translational Oncology, Xuzhou Medical University, Linyi, 276000, China; Postgraduate Training Base of Linyi People's Hospital, Guangzhou University of Chinese Medicine, Linyi, China; Department of Hematology, Linyi People's Hospital, Linyi, 276000, China; Linyi Key Laboratory of Tumor Biology, Linyi, 276000, China.

International immunopharmacology
|September 30, 2025
PubMed
概括

聚林I (PPI) 通过激活caspase-6/ZBP1/NLRP3通路,有效触发扩散型大B细胞淋巴瘤 (DLBCL) 的细胞死亡,为化学疗法耐药淋巴瘤治疗提供了潜在的新途径.

关键词:
卡斯帕斯-6/ZBP1/NLRP3信号通路的使用扩散大的B细胞淋巴瘤.多种类型 I 多种类型 I热性灭症 (Pyroptosis) 是一种

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