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Updated: Jan 16, 2026

Activated Cross-linked Agarose for the Rapid Development of Affinity Chromatography Resins - Antibody Capture as a Case Study
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简化离子交换染色学过程的开发,用于治疗单克隆抗体净化

Wing Yee Lau1, Xue Mi1, Alex Dumont1

  • 1Purification Process Development, Product Development, Science & Technology - Biologics, AbbVie Bioresearch Center, Worcester, MA 01605USA.

Journal of chromatography. A
|September 30, 2025
PubMed
概括

这项研究评估了用于单克隆抗体 (mAb) 净化的阴离子交换 (CEX) 染色学树脂,确定Poros XS作为高容量和杂质清除的优越选择. 这些发现简化了树脂选择和工艺开发,以高效地制造治疗性蛋白质.

关键词:
精细的净化净化方法高通量选的高通量选建模模型 建模模型过程稳固性 过程稳固性mAbAb 在线观看

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