之前的制度化与在厌恶性学习过程中,核和杏仁体之间的功能连接性提高有关
Benjamin M Rosenberg1, João F Guassi Moreira2, Adriana S Méndez Leal3
1Neuroscience Department, Pomona College, Claremont, CA, USA.
Developmental cognitive neuroscience
|September 30, 2025
概括
制度化影响青少年大脑发育,增加威胁电路的响应能力. 这可能导致内化障碍,但NAcc-杏仁体连接性差异可能会随着年龄的增长而减少.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 儿童精神病学 儿童精神病学
背景情况:
- 制度化是一个重要的早期逆境,与青春期内化障碍有关.
- 发展理论表明,学习差异通过回避行为调解了逆境和内化障碍之间的联系.
- 对这些发展模型的实证测试仍然有限.
研究的目的:
- 研究机构化后内化障碍的神经生物学基础.
- 检查以前住院的青少年大脑威胁电路中的功能连接.
- 探索制度化,年龄和内化症状之间的关系.
主要方法:
- 使用fMRI扫描来评估在厌恶性学习任务期间的大脑活动.
- 参与者包括先前住院 (PI) 和对比年轻人.
- 使用父报告尺度测量了内化症状;分析了核 (NAcc) 和杏仁体之间的功能连接.
主要成果:
- 与对照组相比,以前住院的年轻人表现出较高的NAcc-杏仁体功能连接性.
- 这种高度的连接性在PI年轻人中在青春期早期更为明显.
- 在收养后,连接差异可能会随着年龄的增长而减少.
结论:
- 制度化可能会改变神经发育,提高威胁电路对威胁和安全刺激的响应能力.
- NAcc-桃体功能连接可能代表一个神经生物学标记,将早期的逆境与内化障碍联系起来.
- 这些连接差异的与年龄相关的减弱表明了制度化后恢复的潜力.
相关概念视频
Role of Amygdala in Memory
1.1K
The amygdala is a small, almond-shaped structure responsible for processing and storing memories, particularly those linked to emotions like fear and stress. It plays an essential role in the brain's response to emotionally significant events and often enhances memory formation by triggering stress hormone release. The amygdala is vital for encoding and retrieving memories associated with fear or stress, a process that is adaptive by helping organisms avoid dangerous situations.
One of the...
One of the...
1.1K
Functional Brain Systems: Limbic System
6.5K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
6.5K
Associative Learning
1.2K
Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
Classical conditioning, also known...
1.2K
Classical Conditioning in Daily Life
2.1K
Classical conditioning, a fundamental principle of associative learning, explains various phenomena observed in daily life, such as fear development, the placebo effect, taste aversion, and drug habituation. These applications demonstrate the profound impact of associative learning on human behavior and physiological responses.
John B. Watson and Rosalie Rayner famously demonstrated the development of fear through classical conditioning in their experiment with Little Albert. They paired the...
John B. Watson and Rosalie Rayner famously demonstrated the development of fear through classical conditioning in their experiment with Little Albert. They paired the...
2.1K
Real-World Application of Classical Conditioning
1.3K
Classical conditioning not only includes the initial pairing of stimuli but also extends to more complex forms, such as higher-order conditioning. Higher-order conditioning involves creating associations beyond the primary conditioned stimulus, resulting in a chain of conditioned responses.
Higher-order, or second-order, conditioning occurs when a neutral stimulus becomes associated with an already established conditioned stimulus through repeated pairings. For instance, if a dog has been...
Higher-order, or second-order, conditioning occurs when a neutral stimulus becomes associated with an already established conditioned stimulus through repeated pairings. For instance, if a dog has been...
1.3K
Higher Mental Functions of Brain: Learning and Memory
1.9K
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
1.9K


