在自闭症和神经类型女孩的青春期发育期间检查雄激素和雌激素配置
Blythe A Corbett1, Rachel Calvosa2, Jaclyn Tamaroff3
1Vanderbilt University Medical Center, Department of Psychiatry and Behavioral Sciences, Nashville, TN, United States; Vanderbilt University Medical Center, Vanderbilt Kennedy Center, Nashville, TN, United States; Vanderbilt University, Department of Psychology, Nashville, TN, United States.
Hormones and behavior
|September 30, 2025
概括
这项研究发现,自闭症和神经类型女孩之间的青春期开始或激素水平没有显著差异. 需要进一步的研究来了解青春期在自闭症谱系障碍 (ASD) 中的荷尔蒙变化.
科学领域:
- 神经发育障碍 神经发育障碍
- 内分泌学 在内分泌学.
- 儿科卫生保健 儿科卫生保健
背景情况:
- 自闭症谱系障碍 (ASD) 理论上受性激素的影响,特别是在青春期.
- 之前的研究表明,自闭症和神经类型女孩之间的青春期开始可能存在差异.
- 这项研究调查了与青春期和年龄相关的荷尔蒙特征,在有或没有自闭症的女性中.
研究的目的:
- 为了检查自闭症和神经型女孩之间的青春期开始的差异.
- 为了研究性激素 (脱乙二硫酸 (DHEA-S),雌激素,) 和女性青春期发育之间的关系.
- 探索整个青春期和年龄的荷尔蒙变化中的诊断差异.
主要方法:
- 参与者包括112名患有自闭症的女孩和96名6至12岁的典型发育 (TD) 的女孩.
- 收集唾液样本进行激素检测.
- 使用了非线性最小平方和普通线性回归模型.
主要成果:
- 自闭症和神经型女孩之间没有发现青春期开始的显著差异 (p = 0.692).
- 在青春期或年龄范围内,没有观察到激素变化 (DHEA-S,雌激醇,) 的诊断差异.
- 所有测量的荷尔蒙都显示出与青春期和年龄相关的显著变化 (p < 0.001).
结论:
- 这项横截面研究没有显示出青春期发作或激素形状的群体差异.
- 随着自闭症女孩进入青春期,荷尔蒙变化可能会变得明显.
- 在这个发育阶段,持续的监测和支持对自闭症女孩至关重要.
相关概念视频
Signs of Puberty
1.4K
Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
1.4K
Socioemotional Experience and Gender Development
266
Social-emotional experiences and cultural influences play significant roles in shaping gender development. During middle childhood, from ages 6 to 11, peer groups become dominant in reinforcing gender norms. Children in this age group often align with same-gender peer groups, which actively encourage behaviors that conform to traditional gender roles. For instance, boys may be discouraged from engaging in activities perceived as feminine, reinforcing culturally dictated norms about masculinity...
266
Autism Spectrum Disorder
981
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
981
Modeling in Therapy
381
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
381
Anorexia Nervosa
988
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
988
Cognitive Development During Adolescence
503
During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...
503


