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Updated: Jan 16, 2026

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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Published on: September 8, 2012

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功能性RNA分裂推动了从转子体的类型V CRISPR-Cas系统的进化出现

Shuai Jin1, Zixu Zhu2, Yunjia Li2

  • 1New Cornerstone Science Laboratory, Center for Genome Editing, Laboratory of Advanced Breeding Technologies, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.

Cell
|September 30, 2025
PubMed
概括

转子子编码的TnpB核酶演变成了CRISPR-Cas系统. 研究人员发现了使用分裂RNA导体的转子子-CRISPR中间体 (TranCs),揭示了转子如何产生CRISPR免疫力.

关键词:
在CRISPR-Cas12中由RNA引导的核酶这是一个很好的机会.转换时间功能性RNA分裂基因组编辑转子化

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