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Updated: Jan 16, 2026

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
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Lnk/Sh2b3调节自身免疫性胰岛炎的发病和严重程度,并有助于糖尿病风险

Mari Tenno1,2, Satoshi Takaki3

  • 1Department of Immune Regulation, The Research Center for Hepatitis and Immunology, National Institute of Global Health and Medicine, Japan Institute for Health Security, Chiba, Japan.

Life science alliance
|September 30, 2025
PubMed
概括

Lnk适应蛋白对于调节1型糖尿病 (T1D) 的免疫反应至关重要. 在小鼠中Lnk缺陷通过促进T细胞激活和胰腺β细胞损伤增加了对T1D的易感性.

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