手术后痴呆症与口腔和大面部重建手术后的长期死亡率增加有关
Y Nitta1, T Sanuki2, S Sugino3
1Department of Dental Anaesthesiology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
International journal of oral and maxillofacial surgery
|September 30, 2025
概括
手术后痴呆症 (POD) 在口腔和面外科手术患者的2年生存率显著降低. 早期的POD识别和管理对于改善这一高风险群体的结果至关重要.
科学领域:
- 口腔和牙面部外科手术
- 关键护理医学 关键护理医学
- 老年精神病学是一门精神病学专业.
背景情况:
- 手术后妄 (POD) 是大手术后的一个常见并发症.
- 它对口腔和大面部重建手术后的长期存活的影响尚未得到充分证实.
- 确定POD的术后风险因素对于患者管理至关重要.
研究的目的:
- 确定POD对接受口腔和大面部重建手术的患者2年生存期的影响.
- 在这个患者群体中确定与POD相关的术后风险因素.
主要方法:
- 对65名接受口腔和大面部重建手术的患者进行了回顾性观察性研究.
- 根据精神病学评估,患者被分为POD (n=20) 和非POD (n=45) 组.
- 使用卡普兰-梅尔曲线和考克斯比例危险模型进行生存分析.
主要成果:
- 在30.8%的患者中发生POD.
- 两年生存率在POD组 (60%) 与非POD组 (87%) (P=0.009) 相比显着较低.
- POD是降低生存率的独立风险因素 (HR 3.40,P=0.034);没有发现有意义的外科手术预测因素.
结论:
- POD与口腔和大面部重建手术后的长期存活率大幅下降有关.
- 早期识别和管理POD对于改善这一高风险人群的结果至关重要.
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