淋巴 edem:当前的现实世界前性评估.
Angus J Lloyd1, Alison Johnston1, Geraldine MacGregor1
1Breast Centre North West, Letterkenny University Hospital, Ireland; Donegal Clinical Research Academy, Donegal, Ireland.
概括
在有症状的患者中,评估了与乳腺癌相关的淋巴胀 (BCRL) 发生率. 这项研究发现该机构的BCRL发病率较低,低于国际标准,提供了关于诊断和管理的真实数据.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 淋巴 edem 研究 研究 淋巴 edem 研究
背景情况:
- 与乳腺癌相关的淋巴 (BCRL) 是一个重大的临床挑战.
- 发病率各不相同,较高的发病率与更广泛的淋巴结剖析相关 (例如,股淋巴结剖析[ALND]与哨兵淋巴结活检[SLNB]).
研究的目的:
- 为了前性地评估在接受手术的有症状的乳腺癌患者中BCRL的发生率.
- 根据外科手术 (SLNB vs. ALND) 和骨分期程度 (有或没有I/II级骨淋巴结解剖) 来评估BCRL发生率.
主要方法:
- 从2016年1月到2019年7月进行的前性单中心研究.
- 包括147名有症状的乳腺癌患者.
- 使用标准化手臂周长测量和在手术前,1年和2年后的手术前,1年和2年后的水位移动来评估肢体体积.
主要成果:
- 2年后的BCRL总体发生率为6.1% (手臂周长) 和15.7% (水位移).
- 根据手术组的发病率有所不同:单独SLNB (4.3%周长,10.6%水位),SLNB + RLNR (33.3%周长,33.3%水位),单独ALND (11.5%周长,15.4%水位),ALND + RLNR (4.2%周长,33.3%水位).
- 在SLNB和ALND群体之间,广泛的局部切除率和淋巴结切除数量的显著差异.
结论:
- 该研究提供了关于BCRL诊断和乳腺癌患者发病率的真实数据.
- 与国际基准相比,该机构的BCRL发病率较低.
- 这些发现强调了测量方法和手术方法在BCRL评估中的重要性.
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